Structural Protein mRNA

Introduction

Structural function is one of biological functions of proteins. Structural proteins mainly constitute the bones, skin and ligaments in the organism, whose functions are associated with cell growth and differentiation, regeneration of tissues and infiltrative growth of tumours. In general, structural proteins include collagen, intermediate filament proteins, fibronectin, integrin, elastin, actin and keratin. Creative Biolabs offers a variety of mRNA products capable of encoding many types of structural proteins, which can be applied to the study of biological mechanisms of structural proteins, the study of wound repair functions, the investigation of tumour-related regulatory mechanisms and the development of gene therapy drugs. With IVTScrip™ synthesis platform and professional mRNA design team, our structural protein mRNA products are all of high quality, high translation rate and low delivery cycle. Furthermore, we offer purification processes and mass spectrometry characterisation at all stages to ensure the purity and authenticity of our structural protein mRNA products.

In addition, Creative Biolabs also offers customized services for mRNAs that can encode specific structural proteins. With a team of experts with over 10 years of experience in mRNA synthesis, we are able to design and develop the most suitable synthetic routes and protocols according to the project requirements you provide. Our customisation services include optimisation of reaction components (DNA template, enzyme, nucleotide and buffer components), identification of promoter systems, selection of modification types, mRNA purification and mass spectrometry characterisation. At Creative Biolabs, customers' selections for customization will also be considered. If you are interested in our products, please feel free to contact us.

Product List

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Product Features

• Strict Quality Control Standards
  • Multiple quality control standards.
  • High stability and batch-to-batch consistency.
  • Excellent purity and stability profile.
• Efficient and Time-saving
  • Pre-designed capping and poly (A) tail modification.
  • Shorter turnaround time.

Application

• Cytoskeleton and Movement Studies: Structural protein mRNAs, such as those coding for actin and tubulin, play pivotal roles in the formation and regulation of the cytoskeleton. Studying the mRNA expression and regulatory mechanisms of these proteins can reveal how cells change shapes, achieve movement, and correctly distribute genetic material during cell division. By controlling the expression of structural protein mRNA, scientists can simulate cellular behavior under disease conditions in experiments, providing new strategies for the prevention and treatment of diseases.
• Tissue Engineering and Regenerative Medicine: In tissue engineering and regenerative medicine, structural protein mRNAs are crucial for directing the synthesis of scaffold proteins like collagen, elastin, and fibronectin. For example, by promoting the expression of key structural proteins such as actin and collagen, the wound healing process and tissue regeneration can be accelerated. In addition, using structural protein mRNA, tissues with specific structures and functions, such as skin, muscle, or bone, can be cultured in vitro. This is of great significance for replacing damaged tissues or organs, conducting drug tests, and building disease models.
• Disease Mechanisms and Treatment: Abnormalities in structural protein mRNA expression or function are linked to various diseases, including muscular dystrophies, neurodegenerative disorders, and certain cancers. By studying the expression patterns and regulatory mechanisms of these protein mRNAs, scientists can identify the molecular mechanisms of diseases, discover new biomarkers, and develop therapeutic methods targeting these proteins or their regulatory factors. For example, gene therapies or small molecule drugs targeting specific structural protein mRNA expression abnormalities can restore normal protein function, treating or alleviating the symptoms of related diseases.
• Development of Biomaterials: Structural protein mRNAs are exploited in the development of biomaterials by guiding the synthesis of specific proteins that can self-assemble into nanostructures or scaffolds. Scientists can design new biocompatible materials by simulating the assembly and function of structural proteins in nature for use in drug delivery and tissue regeneration.

Q&A