Creative Biolabs is one of the well-recognized experts who are professional in applying advanced platforms for the development of drug delivery systems. Now we are proud to offer a series of reagents, such as hydrogenated soy phosphatidylcholine to achieve more functions.
In oral drug delivery, coatings and matrix systems are always used to control the drug release rates from the dosage forms. Hydrogenated soy phosphatidylcholine, also known as hydrogenated soybean phosphatidylcholine or HSPC, now has been investigated as a promising excipient for matrix tablets formation. With a series of advantages, such as excellent flow properties and processability by compression, HSPC matrices present great potential to extend drug release regarding drug loading and solubility for oral drug delivery of water-soluble drugs. What's more, HSPC can be used in the preparation of lipid nanoparticles.
Phospholipon 80 H and Phospholipon 90 H are both hydrogenated soy phosphatidylcholine. Phospholipon 90 H (P90H) is a novel lipoid that has been used in the construction of a PEGylated microscopic lipospheres delivery system for gentamicin. Multiple physical and chemical characterization tests showed that the encapsulation efficiency (EE%) and loading capacity (LC) is significantly improved. Among them, the low crystallinity of phospholipid 90 H may be an important contributing factor. In summary, using phospholipid 90 H-based lipid drug delivery systems, the problem of poor absorption and gentamicin stability in the oral formulation can be solved.
Equipped with world-leading technology platforms and professional scientific staff, we are pleased to offer the most qualified products for our customers all over the world. If you are interested in our products or services, please do not hesitate to contact us for more detailed information.
