Researchers from University College London, King’s College London, and Moderna have published a paper in the journal Science Translational Medicine titled: mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinicalRead More…
RNA therapy is a novel therapeutic strategy that leverages RNA molecules to regulate gene expression or induce immune responses. RNA therapy possesses several advantages, such as programmability, diversity, flexibility, and safety, andRead More…
Despite the significant progress made in mRNA delivery based on classical cationic carriers, adverse events inevitably occur, including high inflammation and cellular toxicity, due to the need to compact mRNA through electrostaticRead More…
The research team led by Daniel Anderson at the Massachusetts Institute of Technology has published a research paper titled “Combinatorial development of nebulized mRNA delivery formulations for the lungs” in the journalRead More…
In recent years, messenger ribonucleic acid (mRNA) therapy has garnered significant interest and has been developed for the treatment of a range of diseases, including rare genetic disorders, neurodegenerative diseases, inflammation, cancer,Read More…
Lyme disease is the most common vector-borne infectious disease in the United States, in part because there is currently no human vaccine against it. In a recent research report titled “Development ofRead More…
On October 2, 2023, the Nobel Committee announced that this year’s Nobel Prize in Physiology or Medicine would be jointly awarded to Katalin Karikó and Drew Weissman for their discoveries in nucleosideRead More…
In a recent study, researchers from the Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania developed a proof-of-concept model for delivering gene-editing tools to treatRead More…
mRNA-based cancer therapies hold immense potential to revolutionize cancer treatment. However, there are several challenges that need to be addressed for the clinical use of mRNA in cancer therapy. mRNA itself isRead More…
Proteins in organisms are primarily composed of 20 common amino acids encoded by 61 codons. Except for methionine and tryptophan, the other amino acids are encoded by 2 to 6 different codons.Read More…