Advanced delivery systems that overcome biological barriers while maintaining safety and efficacy are essential for the success of mRNA-based therapies. Creative Biolabs integrate recent advancements and challenges facing mRNA delivery systems intoRead More…
Introduction mRNA is the interlocutor between the genetic code and the protein machine that powers life, part of the dance of molecular biology. The molecule is recently a superstar in the creationRead More…
What’s the Next Frontier in Medicine? These last couple of years, mRNA therapies have been a long-running great medical development, along with super-fast COVID-19 vaccines. These vaccines already demonstrated what mRNA can do,Read More…
In a recent study, researchers from the Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania developed a proof-of-concept model for delivering gene-editing tools to treatRead More…
Nucleic acid-based drugs are very adaptable and may encode a wide range of therapeutic proteins for treatment, prevention, or vaccine. Currently, the development and improvement of viral vectors such as lentivirus andRead More…
Phenylketonuria (PKU) is an autosomal recessive disease caused by the abnormal metabolism of phenylalanine (Phe). PKU is caused by a mutation in the phenylalanine hydroxylase (PAH) gene. This gene produces a liverRead More…
Advantages mRNA has a unique position in gene therapy and protein therapy, combining the advantages of both therapies while circumventing the challenges faced by both. For example, the difficulty of producing multimericRead More…
With the rapid development of tumor immunotherapy, drugs have been approved at PD-1, CTLA-4, PD-L1, LAG-3 and other immune checkpoints, bringing a lot of enthusiasm for research and development to the industry.Read More…
mRNA therapy was first used in tumor therapy by injecting mRNA encoding specific proteins such as cytokines into the tumor to intrigue the immune response. However, it still faces the problems ofRead More…