In a recent study, researchers from the Children’s Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania developed a proof-of-concept model for delivering gene-editing tools to treatRead More…
Nucleic acid-based drugs are very adaptable and may encode a wide range of therapeutic proteins for treatment, prevention, or vaccine. Currently, the development and improvement of viral vectors such as lentivirus andRead More…
Phenylketonuria (PKU) is an autosomal recessive disease caused by the abnormal metabolism of phenylalanine (Phe). PKU is caused by a mutation in the phenylalanine hydroxylase (PAH) gene. This gene produces a liverRead More…
Advantages mRNA has a unique position in gene therapy and protein therapy, combining the advantages of both therapies while circumventing the challenges faced by both. For example, the difficulty of producing multimericRead More…
With the rapid development of tumor immunotherapy, drugs have been approved at PD-1, CTLA-4, PD-L1, LAG-3 and other immune checkpoints, bringing a lot of enthusiasm for research and development to the industry.Read More…
mRNA therapy was first used in tumor therapy by injecting mRNA encoding specific proteins such as cytokines into the tumor to intrigue the immune response. However, it still faces the problems ofRead More…