Introduction to Nucleic Acid Drugs Nucleic acid is the general name of DNA and RNA, in which DNA is the basis for storing, copying, and transmitting genetic information, while RNA plays anRead More…
mRNA (messenger RNA), transcribed from a chain of genetic material DNA, is a chain structure molecule containing four bases (A, U, G, and C). If the mRNA encoding the S protein ofRead More…
In recent years, as a new pharmaceutical technology, mRNA has made a breakthrough in the field of infectious diseases and tumor treatment in a short time. However, how to deliver mRNA drugsRead More…
In response to the SARS-CoV-2 pandemic, mRNA vaccines prepared with lipid nanoparticles (LNPs) have been rapidly developed and deployed. Because of the unstable nature of mRNA, the identification of impurities that mayRead More…
mRNA therapy was first used in tumor therapy by injecting mRNA encoding specific proteins such as cytokines into the tumor to intrigue the immune response. However, it still faces the problems ofRead More…
In a new study, researchers from the Massachusetts Institute of Technology, the McGovern Institute for Brain Science, the Howard-Hughes Institute of Medicine, and the Broad Institute developed a platform for delivering molecularRead More…