Optimization Strategy of COVID-19 mRNA Vaccine
Proteins in organisms are primarily composed of 20 common amino acids encoded by 61 codons. Except for methionine and tryptophan, the other amino acids are encoded by 2 to 6 different codons.Read More…
Proteins in organisms are primarily composed of 20 common amino acids encoded by 61 codons. Except for methionine and tryptophan, the other amino acids are encoded by 2 to 6 different codons.Read More…
The mRNA COVID-19 vaccine plays a key role in the fight against COVID-19. Because of its rapid production ability and promising results in a number of clinical studies, vaccines and treatments basedRead More…
A variety of vaccines have been approved to prevent COVID-19, including two mRNA vaccines, Comirnty (BNT162b2) developed by Pfizer / BioNTech and Spikevax (mRNA-1273) developed by Moderna. The mRNA vaccine has playedRead More…
Nucleic acid-based drugs are very adaptable and may encode a wide range of therapeutic proteins for treatment, prevention, or vaccine. Currently, the development and improvement of viral vectors such as lentivirus andRead More…
The COVID-19 pandemic makes the mRNA vaccine become the focus of global researchers. The rapid development of the COVID-19 vaccine benefits from years of research on using mRNA vaccines as a cancerRead More…
Lung-related diseases, including viral infections, tumors, and hereditary diseases, pose a great threat to human life and health. However, the cure for these diseases is still limited. With the development of variousRead More…
At the 2022 annual meeting of the American Association for Cancer Research (AACR), BioNTech released its phase 1 clinical data of CAR-T + CARVac in the treatment of Claudin6 (CLDN6) positive solidRead More…
T cell antigen receptor (TCR) signals can help control the development, activation, and survival of T cells by involving multiple layers and mechanisms regulated by a variety of genes. M6-methyladenosine (m6A) isRead More…
Phenylketonuria (PKU) is an autosomal recessive disease caused by the abnormal metabolism of phenylalanine (Phe). PKU is caused by a mutation in the phenylalanine hydroxylase (PAH) gene. This gene produces a liverRead More…
Advantages mRNA has a unique position in gene therapy and protein therapy, combining the advantages of both therapies while circumventing the challenges faced by both. For example, the difficulty of producing multimericRead More…