Niren Murthy of the University of California, Berkeley, Wang Aijun of the University of California, Davis, and others published a research paper titled: Acid-degradable lipid nanoparticles enhance the delivery of mRNA in the Nature sub-journalRead More…
mRNA-4157 (V940) is a personalized tumor mRNA vaccine. By utilizing lipid nanoencapsulation technology, mRNA-4157 can deliver up to 34 tumor-specific antigens (also called tumor neoantigens) that are specifically tailored for tumor patients into theRead More…
In recent years, RNA vaccines have attracted widespread attention for their potential in cancer treatment. With the successful rollout of COVID-19 vaccines, RNA technology has demonstrated its potential for rapid development andRead More…
Li Bowen of the University of Toronto and Daniel Anderson of the Massachusetts Institute of Technology published a research paper entitled “Accelerating ionizable lipid discovery for mRNA delivery using machine learning andRead More…
The orthopoxvirus family is a lineage of pathogens that cause severe pox in humans and animals, including members such as monkeypox virus (MPXV), vaccinia virus (CPXV), and the historically notorious smallpox virusRead More…
The primary characteristic of brain aging is the decline in cognitive functions, including episodic memory, working memory, and the speed of information processing. During the aging process of the brain, the structureRead More…
Researchers from University College London, King’s College London, and Moderna have published a paper in the journal Science Translational Medicine titled: mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinicalRead More…
RNA therapy is a novel therapeutic strategy that leverages RNA molecules to regulate gene expression or induce immune responses. RNA therapy possesses several advantages, such as programmability, diversity, flexibility, and safety, andRead More…
Despite the significant progress made in mRNA delivery based on classical cationic carriers, adverse events inevitably occur, including high inflammation and cellular toxicity, due to the need to compact mRNA through electrostaticRead More…
The research team led by Daniel Anderson at the Massachusetts Institute of Technology has published a research paper titled “Combinatorial development of nebulized mRNA delivery formulations for the lungs” in the journalRead More…