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mRNA Services

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.
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Over several years, Creative Biolabs has been a world leader in the discovery and production of mRNA reagents for research and drug development. With dedicated scientists and advanced knowledge of mRNA, Creative Biolabs focuses on advancing mRNA technology to solve challenges that are unique to mRNA drug development, including mRNA biology, chemistry, formulation and delivery, bioinformatics, and protein engineering.

We have set out to create a variety of mRNA services to meet the broad potential applications of mRNA. With our decades of experience in mRNA development, we can design and manufacture the best suitable mRNA for different applications to meet our customers' requirements. For more detailed information, please feel free to contact us or directly send us an online inquiry.

Scope of Service

Creative Biolabs provides the highest quality products and excellent services to support our customers' different requirements in research, clinical, and drug development. We provide complete, innovative solutions and a comprehensive portfolio of mRNA services to help you solve the problems during your research.

Custom mRNA Synthesis

For different lengths of mRNA fragments, Creative Biolabs provides services for the synthesis of custom-designed, highly modified mRNAs using both chemical synthesis and efficient IVT methodology. Simply provide us with the desired sequence of DNA template and we will synthesize high-quality synthetic mRNA and provide QC of mRNA products.

Custom mRNA Modification

Creative Biolabs provides a wide variety of mRNA modification services such as mRNA 5' capping, 3' end of poly(A), and nucleotide modification with a dedication to advancing your programs. Our modification services of mRNA provide high-quality mRNA which is is more efficiently translated and results in higher levels of protein expression in certain translational systems.

Custom Delivery Vehicle for mRNA

Depending on its length, mRNA requires the best-fit delivery vehicle to facilitate cellular uptake and release into the cytoplasm. Creative Biolabs offers a series of delivery vehicles for options, including but not limited to lipid-based vectors, polymer-based vectors, and hybrid vectors.

Custom mRNA-based Cell Reprogramming Service

Creative Biolabs has gained years of experience in mRNA-based cell reprogramming and will offer you the best advice and support to help advance your programs. We are competent to design proper mRNA-based cell reprogramming, including T cell reprogramming, dendritic cell reprogramming, natural killer cell reprogramming, B cell reprogramming, and iPS cell reprogramming.

Custom mRNA Stability Test Service

mRNA stability can have a profound impact on gene expression and, ultimately, on cellular phenotype which leads to speculation on potential novel therapeutic applications. To assess mRNA stability, direct measurements of mRNAs can be performed in several ways at Creative Biolabs, such as actinomycin D-based method, c-fos serum-inducible promoter system, tet-off regulatory promoter system and even specific assay development.

One-stop mRNA Therapeutics Development

With the well-established technology, Creative Biolabs is dedicated to offering one-stop mRNA therapeutics development services to meet your development goal in a time-saving manner. Our one-stop services include mRNA for immunotherapy, genetic diseases, protein replacement therapy, regenerative medicine, therapeutic antibody-coding mRNA, mRNA pharmacology optimization, and mRNA vaccines development.

In Silico mRNA Structure Prediction

In silico prediction and modeling is an important tool used to obtain RNA secondary structure. This method is either a sequence-based prediction or 3D structure-based assessment routines. As an undoubted leader in mRNA services, Creative Biolabs has developed a delicate mRNA modeling platform for RNA 3D structure prediction, analysis, and manipulation.

RNA-Protein Interactions Analysis

RNA-protein interactions can have a profound effect on controlling the spatial and temporal localization of mRNA within a cell and non-coding RNA function. With years of industry experience in mRNA research, Creative Biolabs has developed a variety of methods to comprehensively define RNA-protein interactions. We offer a comprehensive range of RNA-protein interactions analysis services characterized by quality, predictability, delivery, and customization.


Creative Biolabs is one of the well-recognized experts who are professionals in offering high-quality mRNA-based assays. According to the different goals and expected applications, different assays may need to be designed and prepared. With our rich experience in mRNA-based assay technology, Creative Biolabs is now offering a variety of mRNA-based assay services for our customers, which can solve your particular project requirements.

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Creative Biolabs has developed a complete LPR technology platform for manufacturing commercial mRNA products. This includes using histidylated LPR technology to modify the mRNA, encoding various tumor antigens, with specific liposomes and polymers. A mannosylated LPR technology is also used for improving transfection efficiency in mRNA treatments. This efficient workflow lowers costs and speeds up mRNA therapeutics development.

The illustration of LPR composition. Fig.1 The illustration of LPR composition. (Pichon, 2013)

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Custom Services FAQs

Q: How long will it take to get a response after I submit an online request or send an email?

A: Our customer manager will contact you within 24 hours.

Q: Do I need to submit multiple requests if I have multiple customization needs?

A: No, one-stop service is our feature. To save your time, we will assign a specific customer manager for you, and you can communicate with him about all the problems and understand the progress of all projects.

Q: Do you provide delivery notifications?

A: Yes, we will send you an email notification after your order has been picked up by the shipping carrier.

Featured mRNA Products

All products and services are For Research Use Only and CANNOT be used in the treatment or diagnosis of disease.