Phenylketonuria (PKU) is an autosomal recessive disease caused by the abnormal metabolism of phenylalanine (Phe). PKU is caused by a mutation in the phenylalanine hydroxylase (PAH) gene. This gene produces a liverRead More…
Advantages mRNA has a unique position in gene therapy and protein therapy, combining the advantages of both therapies while circumventing the challenges faced by both. For example, the difficulty of producing multimericRead More…
An emerging field of mRNA technology is in vivo encoding immune proteins or immunomodulatory proteins that can be used therapeutically, such as antibodies and cytokines. One of the main challenges of proteinRead More…
With the rapid development of tumor immunotherapy, drugs have been approved at PD-1, CTLA-4, PD-L1, LAG-3 and other immune checkpoints, bringing a lot of enthusiasm for research and development to the industry.Read More…
As the mRNA vaccine has achieved great results in the prevention of COVID-19, it has been widely recognized by global researchers. At the same time, the application prospect of mRNA technology inRead More…
Therapeutic mRNA vaccines have developed rapidly in recent years, and they have attracted wide attention as a new choice for tumor treatment. Through precise sequence design, mRNA vaccines can encode one orRead More…
Introduction to Nucleic Acid Drugs Nucleic acid is the general name of DNA and RNA, in which DNA is the basis for storing, copying, and transmitting genetic information, while RNA plays anRead More…
mRNA (messenger RNA), transcribed from a chain of genetic material DNA, is a chain structure molecule containing four bases (A, U, G, and C). If the mRNA encoding the S protein ofRead More…
Like most vaccines, mRNA vaccines need to be injected with syringes, which can be an obstacle for people who are afraid of needles. If the mRNA vaccine can be delivered orally, itRead More…
In recent years, as a new pharmaceutical technology, mRNA has made a breakthrough in the field of infectious diseases and tumor treatment in a short time. However, how to deliver mRNA drugsRead More…