In response to the SARS-CoV-2 pandemic, mRNA vaccines prepared with lipid nanoparticles (LNPs) have been rapidly developed and deployed. Because of the unstable nature of mRNA, the identification of impurities that mayRead More…
mRNA therapy was first used in tumor therapy by injecting mRNA encoding specific proteins such as cytokines into the tumor to intrigue the immune response. However, it still faces the problems ofRead More…
In a new study, researchers from the Massachusetts Institute of Technology, the McGovern Institute for Brain Science, the Howard-Hughes Institute of Medicine, and the Broad Institute developed a platform for delivering molecularRead More…
The structure of mRNA can be divided into five parts, starting from the 5 ‘end, namely, 5’ cap, 5 ‘non-transcriptional region (UTR), open reading frame encoding antigen, 3’UTR and polyadenine tail. EachRead More…