RNA-protein interactions (RPIs) are central to cellular function, governing processes such as mRNA splicing, translation regulation, and RNA degradation. Dysregulation of these interactions is implicated in diseases ranging from cancer to neurodegenerativeRead More…
Advanced delivery systems that overcome biological barriers while maintaining safety and efficacy are essential for the success of mRNA-based therapies. Creative Biolabs integrate recent advancements and challenges facing mRNA delivery systems intoRead More…
Introduction mRNA is the interlocutor between the genetic code and the protein machine that powers life, part of the dance of molecular biology. The molecule is recently a superstar in the creationRead More…
In life’s circuits, message RNA (mRNA) sits between genetic material and protein synthesis, slipping from DNA to proteins. That’s transcription: the making of mRNA — the job that’s vital for gene expression,Read More…
What’s the Next Frontier in Medicine? These last couple of years, mRNA therapies have been a long-running great medical development, along with super-fast COVID-19 vaccines. These vaccines already demonstrated what mRNA can do,Read More…
Niren Murthy of the University of California, Berkeley, Wang Aijun of the University of California, Davis, and others published a research paper titled: Acid-degradable lipid nanoparticles enhance the delivery of mRNA in the Nature sub-journalRead More…
mRNA-4157 (V940) is a personalized tumor mRNA vaccine. By utilizing lipid nanoencapsulation technology, mRNA-4157 can deliver up to 34 tumor-specific antigens (also called tumor neoantigens) that are specifically tailored for tumor patients into theRead More…
In recent years, RNA vaccines have attracted widespread attention for their potential in cancer treatment. With the successful rollout of COVID-19 vaccines, RNA technology has demonstrated its potential for rapid development andRead More…
Li Bowen of the University of Toronto and Daniel Anderson of the Massachusetts Institute of Technology published a research paper entitled “Accelerating ionizable lipid discovery for mRNA delivery using machine learning andRead More…
The orthopoxvirus family is a lineage of pathogens that cause severe pox in humans and animals, including members such as monkeypox virus (MPXV), vaccinia virus (CPXV), and the historically notorious smallpox virusRead More…