mRNA (messenger RNA), transcribed from a chain of genetic material DNA, is a chain structure molecule containing four bases (A, U, G, and C). If the mRNA encoding the S protein ofRead More…
Like most vaccines, mRNA vaccines need to be injected with syringes, which can be an obstacle for people who are afraid of needles. If the mRNA vaccine can be delivered orally, itRead More…
In recent years, as a new pharmaceutical technology, mRNA has made a breakthrough in the field of infectious diseases and tumor treatment in a short time. However, how to deliver mRNA drugsRead More…
In response to the SARS-CoV-2 pandemic, mRNA vaccines prepared with lipid nanoparticles (LNPs) have been rapidly developed and deployed. Because of the unstable nature of mRNA, the identification of impurities that mayRead More…
mRNA therapy was first used in tumor therapy by injecting mRNA encoding specific proteins such as cytokines into the tumor to intrigue the immune response. However, it still faces the problems ofRead More…
In a new study, researchers from the Massachusetts Institute of Technology, the McGovern Institute for Brain Science, the Howard-Hughes Institute of Medicine, and the Broad Institute developed a platform for delivering molecularRead More…
The structure of mRNA can be divided into five parts, starting from the 5 ‘end, namely, 5’ cap, 5 ‘non-transcriptional region (UTR), open reading frame encoding antigen, 3’UTR and polyadenine tail. EachRead More…