07Dec/22

For mRNA-LNP Therapeutics Research: Novel FNP Platform Presents Enhanced Stability

December 7, 2022mRNA Therapy ResearchmRNA Deliverycblmrna

Lung-related diseases, including viral infections, tumors, and hereditary diseases, pose a great threat to human life and health. However, the cure for these diseases is still limited. With the development of variousRead More…

10Oct/22

BioNTech’s CAR-T + CARVa Therapy has Reduced Clinical Effects on Solid Tumors But Remarkable Effects on Testicular Cancer

October 10, 2022mRNA Therapy News, mRNA Therapy ResearchCAR-T Therapy, CARVa Therapy, mRNA Vaccinescblmrna

At the 2022 annual meeting of the American Association for Cancer Research (AACR), BioNTech released its phase 1 clinical data of CAR-T + CARVac in the treatment of Claudin6 (CLDN6) positive solidRead More…

14Sep/22

Studies Revealed the Vital Function of m6A Modification in T Cells

September 14, 2022mRNA Therapy Researchm6A Modification, mRNA Modificationcblmrna

T cell antigen receptor (TCR) signals can help control the development, activation, and survival of T cells by involving multiple layers and mechanisms regulated by a variety of genes. M6-methyladenosine (m6A) isRead More…

31Jul/22

New insight! Research Progress of mRNA Replacement Therapy for Phenylketonuria

July 31, 2022mRNA Therapy ResearchmRNA therapy, PKUcblmrna

Phenylketonuria (PKU) is an autosomal recessive disease caused by the abnormal metabolism of phenylalanine (Phe). PKU is caused by a mutation in the phenylalanine hydroxylase (PAH) gene. This gene produces a liverRead More…

27Jun/22

Advantages and Potentials of mRNA Therapy

June 27, 2022mRNA Therapy ResearchLNP Nanoparticles, mRNA Delivery, mRNA therapycblmrna

Advantages mRNA has a unique position in gene therapy and protein therapy, combining the advantages of both therapies while circumventing the challenges faced by both. For example, the difficulty of producing multimericRead More…

27Jun/22

The Emerging Field—mRNA Technique in Protein & Cellular Immunotherapy

June 27, 2022mRNA Therapy ResearchCellular Immunotherapy, mRNA Immunotherapycblmrna

An emerging field of mRNA technology is in vivo encoding immune proteins or immunomodulatory proteins that can be used therapeutically, such as antibodies and cytokines. One of the main challenges of proteinRead More…

19May/22

mRNA Technique Is Releasing More Potential in Treating Autoimmune Diseases

May 19, 2022mRNA Therapy ResearchLNP Nanoparticles, mRNA Vaccines, mRNA-based Therapeuticcblmrna

As the mRNA vaccine has achieved great results in the prevention of COVID-19, it has been widely recognized by global researchers. At the same time, the application prospect of mRNA technology inRead More…

22Apr/22

Great Progress: Novel mRNA Tumor Vaccines Using Bacterial Outer Membrane Vesicles as Delivery Carriers

April 22, 2022mRNA Therapy ResearchLipid Nanoparticles, mRNA Tumor Vaccinecblmrna

Therapeutic mRNA vaccines have developed rapidly in recent years, and they have attracted wide attention as a new choice for tumor treatment. Through precise sequence design, mRNA vaccines can encode one orRead More…

11Apr/22

Research Review on Nucleic Acid Drug

April 11, 2022mRNA Therapy ResearchmRNA delivery system, mRNA Reviewscblmrna

Introduction to Nucleic Acid Drugs Nucleic acid is the general name of DNA and RNA, in which DNA is the basis for storing, copying, and transmitting genetic information, while RNA plays anRead More…

11Apr/22

Comparison of Two mRNA COVID-19 Vaccines Approved by the FDA

April 11, 2022mRNA Therapy ResearchmRNA vaccinecblmrna

mRNA (messenger RNA), transcribed from a chain of genetic material DNA, is a chain structure molecule containing four bases (A, U, G, and C). If the mRNA encoding the S protein ofRead More…