Reporter Gene mRNA

Introduction

Reporter genes are genes encoding fluorescent proteins that enable the detection of gene expression, which can therefore be used as controls in various types of assay. Creative Biolabs provides well-designed reporter mRNAs that can be readily applied in mRNA-related researches for measuring transfection both in vitro and in vivo. Besides the part of CDS, we offer various options on each one reporter mRNA transcript in terms of the 5'-Capping (e.g. Cap0, Cap1, ARCA, etc.), 3'-tailing (e.g. 30 nt-polyA, 120 nt-polyA, etc.), modifications for single bases (e.g. 5-Methoxy-U, Cyanine 5-U, etc.).

Besides the predesigned reporter mRNA products, custom IVT mRNA synthesis is also available at Creative Biolabs for reporter genes with specific features which are not in our increasingly developed inventory of mRNA transcript products. The custom synthesis can be performed using the template DNA either from clients or in-house at Creative Biolabs. If you are interested in our products, please feel free to contact us.

Product List

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Product Features

• Strict Quality Control Standards
  • Multiple quality control standards.
  • High stability and batch-to-batch consistency.
  • Excellent purity and stability profile.
• Efficient and Time-saving
  • Pre-designed capping and poly (A) tail modification.
  • Shorter turnaround time.

Application

• Gene Expression Studies: Scientists use reporter genes to indicate if a particular gene has been taken up and expressed in the cell, allowing for easy and rapid quantification of gene expression.
• Cell Tracing Experiments: Cells can be marked with a reporter gene, allowing researchers to track and locate them within a larger population of cells, or even within a living organism.
• Drug Discovery and Development: Reporter gene assays are frequently used in high-throughput screening for drug discovery. They provide a quick and convenient way of sorting out compounds that affect gene expression.
• Protein-Protein Interaction Studies: The reporter gene can be used in fusion with a protein of interest to study protein-protein interaction.
• Gene therapy development: Reporter genes can be used to monitor the presence and expression of therapeutic genes.
• Studying biological processes: They can be used to study different biological processes like cell differentiation, cell division, cell to cell communication and understanding cellular responses to environmental conditions.
• Promoter analysis: If a reporter gene is downstream of a promoter, the reporter gene's expression can be used to determine the activity of the promoter.

Q&A