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Custom mRNA Synthesis

Cytokine Receptor mRNA

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Introduction Product List Product FeaturesApplication Q&A

Introduction

Cytokine receptors are transmembrane proteins that bind to cytokines to exert their biological effects which are mainly composed of extracellular, transmembrane and cytoplasmic regions. Cytokine receptors include interleukin receptors, interferon receptors, tumour necrosis factor superfamily receptors, colony-stimulating factor receptors and chemokine receptors, which are used to initiate cytokine-mediated stimulation of cell signalling. Creative Biolabs offers a range of high quality mRNA products encoding cytokine receptor proteins that can assist you in your research into cytokine receptor-mediated signalling mechanisms and related diseases, and provide new ideas for gene therapy. In addition to providing different types, we offer different nucleoside modification strategies (Pseudo-UTP, N1-Methylpseudo-UTP, 5-Methoxy-UTP, 2-Thio-UTP, etc.) for the same type of mRNA product to best suit your project needs. All cytokine receptor mRNA products are carefully designed and synthesised by experienced experts on advanced IVTScrip™ platform.

Considering diversity of cytokine receptor type and mRNA nucleoside modification strategy, Creative Biolabs also offers customised services for mRNA products. You can provide the DNA template directly and our experts will ultimately optimise a translationally efficient route for the mRNA synthesis. If the template is unknown, simply inform us of your project requirements and our team will provide you with a range of customised synthesis routes starting with template design. The entire custom synthesis process is carried out under QC standards, ensuring higher purity and better quality cytokine receptor mRNA products. If you are interested in our products, please feel free to contact us.

Product List

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Product Features

  • Strict Quality Control Standards
    • Multiple quality control standards.
    • High stability and batch-to-batch consistency.
    • Excellent purity and stability profile.
  • Efficient and Time-saving
    • Pre-designed capping and poly (A) tail modification.
    • Shorter turnaround time.

Application

  • Immunological Research and Vaccine Development: Research on cytokine receptor mRNA significantly contributes to understanding how the immune system recognizes and responds to pathogens. By studying the expression and regulation of cytokine receptors, scientists can identify how different immune cells are activated during infection or vaccination. They can then develop effective vaccines based on specific cytokines.
  • Cancer Research: The study of cytokine receptor mRNA in cancer research helps to understand tumor immunology and develop immunotherapies. Cytokine receptors on tumor cells and immune cells within the tumor microenvironment play pivotal roles in tumor growth, metastasis, and the immune evasion mechanism of cancer cells. Researchers can focused on the role of cytokine receptor mRNA in the tumor microenvironment, particularly how tumor cells manipulate cytokine signaling to suppress immune surveillance.
  • Autoimmune Diseases: Autoimmune diseases arise from an aberrant immune response against self-antigens, often involving dysregulated cytokine signaling. By studying the mRNA expression of cytokine receptors in autoimmune conditions, researchers can identify potential targets for therapeutic intervention. For example, in rheumatoid arthritis, studies have shown altered expression of cytokine receptor mRNAs in affected tissues, contributing to chronic inflammation and joint damage. Therapeutic strategies targeting the mRNA expression of specific cytokine receptors have been developed to reduce inflammation and halt disease progression, demonstrating the potential of this research in developing treatments for autoimmune diseases.
  • Regenerative Medicine: Cytokine receptor mRNA is also significant in regenerative medicine, where understanding cytokine signaling pathways can help in tissue repair and regeneration. Cytokines and their receptors are involved in stem cell differentiation, angiogenesis, and the healing process. By manipulating the expression of cytokine receptor mRNAs, researchers were able to enhance the regenerative capacity of stem cells, offering promising avenues for repairing damaged tissues and organs.

Q&A

Q1: What are cytokine receptors, and what role do they play in cell signaling?

A: Cytokine receptors are transmembrane proteins that bind to cytokines to exert biological effects, mainly composed of extracellular, transmembrane, and cytoplasmic regions. They are crucial for initiating cytokine-mediated stimulation of cell signaling.

Q2: Which types of cytokine receptors are available for research through Creative Biolabs?

A: Creative Biolabs offers a range of high-quality mRNA products encoding cytokine receptor proteins such as interleukin receptors, interferon receptors, tumor necrosis factor superfamily receptors, colony-stimulating factor receptors, and chemokine receptors.

Q3: How can cytokine receptor mRNA products be customized for specific research needs?

A: Our company offers custom mRNA synthesis, including various nucleoside modification strategies like Pseudo-UTP and N1-Methylpseudo-UTP, to best suit project needs, whether providing a DNA template directly or starting with template design for unknown sequences.

Q4: What quality control measures are in place for cytokine receptor mRNA synthesis?

A: The custom synthesis process is carried out under strict QC standards to ensure higher purity and better quality of the cytokine receptor mRNA products.

Q5: What applications are cytokine receptor mRNA products intended for?

A: These mRNA products are designed for research into cytokine receptor-mediated signaling mechanisms, related diseases, and can provide new ideas for gene therapy.

Q6: What role do cytokine receptor mRNA transcripts play in immune response regulation?

A: They serve as templates for the production of cytokine receptors, which are proteins on the surface of cells that bind to cytokines. These interactions can activate or inhibit immune cell functions, influencing inflammation, cell proliferation, and apoptosis. Understanding the regulation of these transcripts can help in deciphering the mechanisms of immune response and in designing therapies for immune-related disorders.

Q7: How do variations in cytokine receptor mRNA transcripts affect susceptibility to autoimmune diseases?

A: Cytokine receptor mRNA variations may disrupt immune functioning, increase autoimmune disease susceptibility, and aid in discovering personalized medicine strategies.

Q8: What is the impact of post-transcriptional modifications of cytokine receptor mRNA on their function?

A: Post-transcriptional modifications of cytokine receptor mRNA, such as splicing, editing, and polyadenylation, can significantly impact their function. These modifications can alter mRNA stability, localization, and translational efficiency, ultimately affecting the levels and activity of cytokine receptors.

Q9: How do cytokine receptor mRNA transcripts vary between different cell types and tissues?

A: Cytokine receptor mRNA transcripts vary between cell types and tissues, reflecting their unique functions and cytokine responsiveness. This variation influences tissue-specific immune responses and the development of targeted therapies.

Product type mRNA
Transcript SUSD2
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD195
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CDW198
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD269
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD197
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CCR6
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript IL7R
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CXCR6
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CXCR4
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript IL17Ra
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript Podoplanin
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CCR7
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD127
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD25
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript TNFR2
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CCR3
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD123
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript IL1RAP
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript SUSD2
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD195
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CDW198
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD269
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD197
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CCR6
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript IL7R
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CXCR6
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CXCR4
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript IL17Ra
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript Podoplanin
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CCR7
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD127
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD25
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript TNFR2
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CCR3
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD123
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript IL1RAP
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript SUSD2
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD195
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CDW198
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD269
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD197
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CCR6
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript IL7R
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CXCR6
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CXCR4
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript IL17Ra
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript Podoplanin
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CCR7
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript SUSD2
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD195
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CDW198
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD269
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CD197
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CXCR6
Category (CDS) Cytokine Receptor
Applications Gene therapy research
Product type mRNA
Transcript CXCR4
Category (CDS) Cytokine Receptor
Applications Gene therapy research