Cytokine Receptor mRNA

Introduction

Cytokine receptors are transmembrane proteins that bind to cytokines to exert their biological effects which are mainly composed of extracellular, transmembrane and cytoplasmic regions. Cytokine receptors include interleukin receptors, interferon receptors, tumour necrosis factor superfamily receptors, colony-stimulating factor receptors and chemokine receptors, which are used to initiate cytokine-mediated stimulation of cell signalling. Creative Biolabs offers a range of high quality mRNA products encoding cytokine receptor proteins that can assist you in your research into cytokine receptor-mediated signalling mechanisms and related diseases, and provide new ideas for gene therapy. In addition to providing different types, we offer different nucleoside modification strategies (Pseudo-UTP, N1-Methylpseudo-UTP, 5-Methoxy-UTP, 2-Thio-UTP, etc.) for the same type of mRNA product to best suit your project needs. All cytokine receptor mRNA products are carefully designed and synthesised by experienced experts on advanced IVTScrip™ platform.

Considering diversity of cytokine receptor type and mRNA nucleoside modification strategy, Creative Biolabs also offers customised services for mRNA products. You can provide the DNA template directly and our experts will ultimately optimise a translationally efficient route for the mRNA synthesis. If the template is unknown, simply inform us of your project requirements and our team will provide you with a range of customised synthesis routes starting with template design. The entire custom synthesis process is carried out under QC standards, ensuring higher purity and better quality cytokine receptor mRNA products. If you are interested in our products, please feel free to contact us.

Product List

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Product Features

• Strict Quality Control Standards
  • Multiple quality control standards.
  • High stability and batch-to-batch consistency.
  • Excellent purity and stability profile.
• Efficient and Time-saving
  • Pre-designed capping and poly (A) tail modification.
  • Shorter turnaround time.

Application

• Immunological Research and Vaccine Development: Research on cytokine receptor mRNA significantly contributes to understanding how the immune system recognizes and responds to pathogens. By studying the expression and regulation of cytokine receptors, scientists can identify how different immune cells are activated during infection or vaccination. They can then develop effective vaccines based on specific cytokines.
• Cancer Research: The study of cytokine receptor mRNA in cancer research helps to understand tumor immunology and develop immunotherapies. Cytokine receptors on tumor cells and immune cells within the tumor microenvironment play pivotal roles in tumor growth, metastasis, and the immune evasion mechanism of cancer cells. Researchers can focused on the role of cytokine receptor mRNA in the tumor microenvironment, particularly how tumor cells manipulate cytokine signaling to suppress immune surveillance.
• Autoimmune Diseases: Autoimmune diseases arise from an aberrant immune response against self-antigens, often involving dysregulated cytokine signaling. By studying the mRNA expression of cytokine receptors in autoimmune conditions, researchers can identify potential targets for therapeutic intervention. For example, in rheumatoid arthritis, studies have shown altered expression of cytokine receptor mRNAs in affected tissues, contributing to chronic inflammation and joint damage. Therapeutic strategies targeting the mRNA expression of specific cytokine receptors have been developed to reduce inflammation and halt disease progression, demonstrating the potential of this research in developing treatments for autoimmune diseases.
• Regenerative Medicine: Cytokine receptor mRNA is also significant in regenerative medicine, where understanding cytokine signaling pathways can help in tissue repair and regeneration. Cytokines and their receptors are involved in stem cell differentiation, angiogenesis, and the healing process. By manipulating the expression of cytokine receptor mRNAs, researchers were able to enhance the regenerative capacity of stem cells, offering promising avenues for repairing damaged tissues and organs.

Q&A