Creative Biolabs is a trusted partner in mRNA services. With decades of experience in mRNA research and development, our scientists can provide both chemical synthesis approach and IVT synthesis strategy of mRNA to meet the unique requirements of every client. Moreover, we can also offer quality control of mRNA products to advance your program and reduce the full discovery and development timeline.
Recently, synthesized mRNA has been developed for cell engineering, CRISPR/Cas9 genome editing, prophylactic vaccines, and therapeutics. Creative Biolabs is committed to providing customers with high-quality mRNA related services. Due to the rise of robust and reliable in vitro transcription (IVT) systems, mRNA can be generated at milligram to multigram scales with lengths ranging from a few hundred nucleotides to greater than 10 kilobases. Additionally, we can also provide a variety of purification options and modification strategies for your clinical needs, and our suite of analytical services allow you to characterize mRNA thoroughly.
When the fragment of mRNA you need is small, we recommend using a chemical synthesis strategy, which is a quick and more economical method to produce a high yield of chemically synthesized mRNA for various applications. Chemically synthesized mRNAs can be synthesized to contain nearly any sequence, and chemical modification desired, and gram quantity yields are possible.
Starting with a DNA template you provide, or with our gene synthesis and template construction, Creative Biolabs produces high-quality long fragments of mRNA by the IVT method for a wide range of uses, from basic research to clinical applications. Our standard process delivers high-quality material for research use, and we provide scale-up process development and custom manufacturing to meet your specific requirements for clinical use.
Fig.1 IVT synthesis of mRNA.
A comprehensive quality control program at Creative Biolabs can ensure mRNA purity and mass spectral analysis. We could confirm the veracity of the manufacturing process and an exceptional and consistent batch-to-batch quality as well as compliance with regulatory requirements. We can also provide additional custom options available per your project requirements.
Due to our experience of chemical synthesis and IVT synthesis, Creative Biolabs supplies custom synthesis services of high-quality mRNA for our customers all over the world. For more information on our custom mRNA synthesis services, please feel free to contact us.
